Intrinsic mutagenesis.pdf

Intrinsic mutagenesis

Burnet Macfarlane

This book is something which almost accidentally has developed very differently from how it was initially planned. The intention was to elaborate the part played by the immune system in ageing with the role of the thymus as central theme. It was to be essentially an expansion of a lecture I gave in 1970 and would inevitably have been concerned with much the same material as Walfords book, The Immunologic Theory of Aging, though from a different slant. What changed its character arose from a series of attempts to find logical connection between two findings that most gerontologists regard as axiomatic: that the lifespan of a mammal is genetically determined, and that the actual process of ageing is an accumulation of genetic error, of somatic mutations. It is possible that the connection is so indirect, circuitous and multiform that generations of detailed and unattractive research will be needed to elucidate it, or, more likely, the whole matter discarded as a non-problem. But a more inspiring approach does seem possible. The working hypothesis, which halfway through its writing became the new central theme of the book, arose when I was a member of a committee appointed by the Australian Academy of Science at the request of the Australian Government to advise on the danger from French nuclear tests in the South Pacific.

Site-directed mutagenesis - Wikipedia

9401166080 ISBN
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Intrinsic mutagenesis.pdf


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Matteo Müller

1975 Sep; 29(3): 583–584. PMCID: PMC1445963. Intrinsic Mutagenesis. A Genetic Approach to Ageing. R.T. Smith, P.A. Miescher, R.A. Good (Eds.), Phytogeny of Immunity, University of Florida Press, Gainesville (1966), pp. 173-189. Google Scholar. (7).

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Intrinsic mutagenesis: A genetic approach to … Intrinsic mutagenesis: A genetic approach to ageing Softcover reprint of the original 1st ed. 1974 Edition

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28 Jan 2020 ... We show that Escherichia coli with a +1-nt frameshift mutation centrally located in rpoB is viable and highly resistant to rifampicin. Spontaneous ... Intrinsic Mutagenesis. Houten: Springer Netherlands,. 1974. Carrel, Alexis. “On the permanent life of tissues outside the organism” Journal of.

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Køb Intrinsic mutagenesis af Burnet MacFarlane som e-bog på engelsk til markedets laveste pris og få den straks på mail. This book is something which almost accidentally has … Mutagenesis (molecular biology technique) - …