The Molecular Biology of Bacterial Virus Systems.pdf

The Molecular Biology of Bacterial Virus Systems

The fact that none of the known DNA polymerases is able to initiate DNA chains but only to elongate from a free 3 -OH group raises the problem of how replication is initiated, both at the replication origin and on Okazaki frag­ ments. It was first shown by A. KORNBERG et al. that a general mechanism to initiate replication is through the formation of an RNA primer catalyzed by RNA polymerases or by a new class of enzymes, the primases (KORNBERG 1980). This mechanism, which can be used in the case of circular DNA molecules or linear DNAs that circularize or form concatemers, cannot be used at the ends of linear DNAs since the RNA primer is removed from the DNA chain, and there is no way of filling the gap resulting at the 5 -ends of the newly synthesized DNA chain. In some cases linear DNA molecules contain a palin­ dromic nucleotide sequence at the 3 -end that allows the formation of a hairpin structure which provides the needed free 3-OH group for elongation. This mechanism, first proposed by CAVALIER-SMITH (1974) for eukaryotic DNA repli­ cation, was shown to take place in several systems (KORNBERG 1980, 1982). Another mechanism to initiate replication consists in the specific nicking of one of the strands of a circular double-stranded DNA, producing a 3-OH group available for elongation (KORNBERG 1980).

Microbes and Infection publishes 10 peer-reviewed issues per year in all fields of ... the molecular biology and cell biology of the crosstalk between hosts (human and ... and microbes (viruses, bacteria, parasites and fungi), including molecular ... determines intoxication in a Caenorhabditis elegans host-pathogen system.

9.21 MB DATEIGRÖSSE
3642731171 ISBN
Englisch SPRACHE
The Molecular Biology of Bacterial Virus Systems.pdf

Technik

PC und Mac

Lesen Sie das eBook direkt nach dem Herunterladen über "Jetzt lesen" im Browser, oder mit der kostenlosen Lesesoftware Adobe Digital Editions.

iOS & Android

Für Tablets und Smartphones: Unsere Gratis tolino Lese-App

Andere eBook Reader

Laden Sie das eBook direkt auf dem Reader im Hugendubel.de-Shop herunter oder übertragen Sie es mit der kostenlosen Software Sony READER FOR PC/Mac oder Adobe Digital Editions.

Reader

Öffnen Sie das eBook nach der automatischen Synchronisation auf dem Reader oder übertragen Sie es manuell auf Ihr tolino Gerät mit der kostenlosen Software Adobe Digital Editions.

Aktuelle Bewertungen

avatar
Sofia Voigt

Molecular virology is the study of viruses on a molecular level. Viruses are submicroscopic ... and as a result viruses have more biological diversity than the rest of the bacterial, plant, and animal kingdoms combined. ... According to this system, viruses are classified into seven classes based on their replication strategy:. A bacteriophage also known informally as a phage is a virus that infects and replicates within bacteria and archaea. The term was derived from "bacteria" and the Greek φαγεῖν (phagein), ... 5 Genome structure; 6 Systems biology; 7 In the environment; 8 Model ... Bacteriophage: Genetics and Molecular Biology (1st ed.) .

avatar
Matteo Müller

We use experimental data but also data derived from natural populations of pathogenic bacteria to describe and categorize virulence phenotypes. Our objective is to explain clinical and/or in vitro virulence phenotypes with bacterial biology by integrating infection biology, epidemiology and omics technologies. Virus - Wikipedia

avatar
Noel Schulze

Understanding their biology, mechanisms of pathogenesis, epidemiology, and ... system are critical to the development of vaccines and antivirals to treat viral ... area are interested in understanding the molecular mechanisms by which bacteria ... 18 Oct 2012 ... Author Summary Bacteria are under constant attack by their viral ... Evasion of a Bacterial Suicide System by RNA–Based Molecular Mimicry Enables ... was supported by grants from the Biotechnology and Biological Sciences ...

avatar
Jason Lehmann

The fact that none of the known DNA polymerases is able to initiate DNA chains but only to elongate from a free 3' -OH group raises the problem of how replication is initiated, both at the replication origin and on Okazaki frag­ ments. It was first shown by A. KORNBERG et al. that a general Molecular Biology of Bacterial Virus Systems Current ...

avatar
Jessica Kohmann

Home | Microbiology and Molecular Biology …