Mass Spectrometry for Drug Discovery and Drug Development.pdf

Mass Spectrometry for Drug Discovery and Drug Development

Facilitates the discovery and development of new, effective therapeutics With coverage of the latest mass spectrometry technology, this book explains how mass spectrometry can be used to enhance almost all phases of drug discovery and drug development, including new and emerging applications. The books fifteen chapters have been written by leading pharmaceutical and analytical scientists. Their contributions are based on a thorough review of the current literature as well as their own experience developing new mass spectrometry techniques to improve the ability to discover and develop new and effective therapeutics. Mass Spectrometry for Drug Discovery and Drug Development begins with an overview of the types of mass spectrometers that facilitate drug discovery and development. Next it covers: HPLC high-resolution mass spectrometry for quantitative assays Mass spectrometry for siRNA Quantitative analysis of peptides Mass spectrometry analysis of biological drugs Applications that support medicinal chemistry investigations Mass spectrometry imaging and profiling Throughout the book, detailed examples underscore the growing role of mass spectrometry throughout the drug discovery and development process. In addition, images of mass spectra are provided to explain how results are interpreted. Extensive references at the end of each chapter guide readers to the primary literature in the field. Mass Spectrometry for Drug Discovery and Drug Development is recommended for readers in pharmaceutics, including medicinal chemists, analytical chemists, and drug metabolism scientists. All readers will discover how mass spectrometry can streamline and advance new drug discovery and development efforts.

AB SCIEX triple quadrupole-linear ion trap mass spectrometers and accurate mass approaches make that goal a reality. – Qual & Quant for the answers you need: ... Oct 15, 2018 ... Because large molecule drug discovery and development is still ... of more pointed technologies such as mass spectrometry (MS) has improved ...

4.76 MB DATEIGRÖSSE
ISBN
Englisch SPRACHE
Mass Spectrometry for Drug Discovery and Drug Development.pdf

Technik

PC und Mac

Lesen Sie das eBook direkt nach dem Herunterladen über "Jetzt lesen" im Browser, oder mit der kostenlosen Lesesoftware Adobe Digital Editions.

iOS & Android

Für Tablets und Smartphones: Unsere Gratis tolino Lese-App

Andere eBook Reader

Laden Sie das eBook direkt auf dem Reader im Hugendubel.de-Shop herunter oder übertragen Sie es mit der kostenlosen Software Sony READER FOR PC/Mac oder Adobe Digital Editions.

Reader

Öffnen Sie das eBook nach der automatischen Synchronisation auf dem Reader oder übertragen Sie es manuell auf Ihr tolino Gerät mit der kostenlosen Software Adobe Digital Editions.

Aktuelle Bewertungen

avatar
Sofia Voigt

Sep 20, 2018 ... ... now being considered during the drug discovery process, some applications of mass spectrometry to early drug development are addressed. Apr 1, 2017 ... PDF | The drug discovery and development process have been enriched by the development and enhancement in the mass spectrometry ...

avatar
Matteo Müller

Mass Spectrometry for Drug Discovery and Drug Development (Wiley Series on Mass Spectrometry Book 46) (English Edition) eBook: Korfmacher, Walter A.: Amazon.de: Kindle-Shop

avatar
Noel Schulze

Facilitates the discovery and development of new, effective therapeutics With coverage of the latest mass spectrometry technology, this book explains how mass spectrometry can be used to enhance almost all phases of drug discovery and drug development, including new and emerging applications. The books fifteen chapters have been written by leading pharmaceutical and …

avatar
Jason Lehmann

Drug discovery & development pipeline Metabolite identification is central to many of the activities in the discovery and development pipeline. From rapid structural identification during the discovery process to provide an early perspective on the metabolically labile sites, or soft spots of a drug candidate, to a more complete

avatar
Jessica Kohmann

Sep 22, 2018 ... Fragment-based drug discovery (FBDD) is a relative new approach to developing new drugs. While high-throughput screening approaches have ...