Ligand Design for G Protein-coupled Receptors.pdf

Ligand Design for G Protein-coupled Receptors

G protein-coupled receptors (GPCRs) are one of the most important target classes in pharmacology and are the target of many blockbuster drugs. Yet only with the recent elucidation of the rhodopsin structure have these receptors become amenable to a rational drug design.
Based on recent examples from academia and the pharmaceutical industry, this book demonstrates how to apply the whole range of bioinformatics, chemoinformatics and molecular modeling tools to the rational design of novel drugs targeting GPCRs.
Essential reading for medicinal chemists and drug designers working with this largest class of drug targets in the human genome.

Ligand Design for G Protein-coupled Receptors. Additional Information. How to Cite. Fredriksson, R. and Schiöth, H. B. (2006) G Protein-coupled Receptors in the Human Genome, in Ligand Design for G Protein-coupled Receptors (ed D. Rognan), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527608249.ch1 . Editor Information. 2. Laboratoire de Pharmacochimie de la …

9.12 MB DATEIGRÖSSE
9783527608263 ISBN
Englisch SPRACHE
Ligand Design for G Protein-coupled Receptors.pdf

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