Chiral Separation Methods for Pharmaceutical and Biotechnological Products.pdf

Chiral Separation Methods for Pharmaceutical and Biotechnological Products

Discusses chiral separations and offers guidance for selecting the optimum method for desired results Chiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development. Considering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into a broad range of topics. Opening with a broad overview of chiral separations, regulatory considerations in drug product development, and basic issues in method development, the book: Covers a variety of modern methods such as gas chromatography, high performance liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis Deals with the impact of chirality on the biological activity of small and large molecules Provides detailed information on useful chiral stationary phases (CSPs) for HPLC Includes handy information on selection of an appropriate CSP, including mechanistic studies Offers strategies for fast method development with HPLC, SFC, and CE Discusses preparatory methods utilized in the pharmaceutical industry With in-depth discussions of the current state of the field as well as suggestions to assist future developments, Chiral Separation Methods for Pharmaceutical and Biotechnological Products is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as students preparing for careers in these fields.

Chiral Screening Methods for Pharmaceutical … Chiral Screening Methods for Pharmaceutical Analysis and Purification in an Industrial Laboratory Chapter · October 2010 with 5 Reads How we measure 'reads'

1.14 MB DATEIGRÖSSE
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Englisch SPRACHE
Chiral Separation Methods for Pharmaceutical and Biotechnological Products.pdf

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Aktuelle Bewertungen

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Sofia Voigt

High throughput analysis enables high throughput ... Chiral chromatography Today, high throughput analysis in the pharmaceutical industry is closely associated with catalyst and enzyme screening for synthetic chemistry, 25 but this was actually one of the last elements of the high throughput experimentation capability build to come into place. Since a major focus of our effort was developing

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Matteo Müller

With in-depth discussions of the current state of the field as well as suggestions to assist future developments, Chiral Separation Methods for Pharmaceutical and Biotechnological Products is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as

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Noel Schulze

Chiral Separation Methods for Pharmaceutical and Biotechnological Products Article in Organic Process Research & Development 15(4):946–946 · June 2011 with 26 Reads How we measure 'reads'

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Jason Lehmann

This book provides readers with an understanding of chiral separations, and offers a handy guide for selecting the best separation method, saving considerable time and cost in product development. It also discusses chiral separations in the biotechnological and pharmaceutical industries, as well as for agriculture and food applications

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Jessica Kohmann

Enantiopurity Assessment of Chiral Switch of … 04.01.2017 · A simple, selective, robust, and rapid enantiospecific HPLC method was developed and optimized for simultaneous determination of ondansetron enantiomers. The chiral separation was performed on Chiralpak AS-3R analytical column (150 mm × 4.6 mm i.d., 3 µm). AD-optimal mixture design methodology was employed to evaluate the influence of solvent mixtures on retention factor of …