Pancreas disorders

Source: Wikipedia. Pages: 33. Chapters: Acinar cell carcinoma of the pancreas, Acute pancreatitis, Autoimmune pancreatitis, Chronic pancreatitis, Cystic fibrosis, Exocrine pancreatic insufficiency, Hemosuccus pancreaticus, Hereditary pancreatitis, Pancreatic abscess, Pancreatic cancer, Pancreatic disease, Pancreatic fistula, Pancreatic mass, Pancreatic pleural effusion, Pancreatic pseudocyst, Shwachman-Bodian-Diamond syndrome, Slones disease. Excerpt: Cystic fibrosis (also known as CF or mucoviscidosis) is an autosomal recessive genetic disorder that affects most critically the lungs, and also the pancreas, liver, and intestine. It is characterised by abnormal transport of chloride and sodium across an epithelium, leading to thick, viscous secretions. The name cystic fibrosis refers to the characteristic scarring (fibrosis) and cyst formation within the pancreas, first recognized in the 1930s. Difficulty breathing is the most serious symptom and results from frequent lung infections that are treated with antibiotics and other medications. Other symptoms, including sinus infections, poor growth, and infertility affect other parts of the body. CF is caused by a mutation in the gene for the protein cystic fibrosis transmembrane conductance regulator (CFTR). This protein is required to regulate the components of sweat, digestive fluids, and mucus. CFTR regulates the movement of chloride and sodium ions across epithelial membranes, such as the alveolar epithelia located in the lungs. Most people without CF have two working copies of the CFTR gene, and both copies must be missing for CF to develop, due to the disorders recessive nature. CF develops when neither gene works normally (as a result of mutation) and therefore has autosomal recessive inheritance. CF is most common among Caucasians

... thiazide diuretics, and azathioprine), lipid (triglyceride) disorders, infections, surgery, or trauma to the abdomen from an accident or injury. Acute pancreatitis is ... At the UPMC Pancreas Center of Excellence, we're making great strides to ... of other world-renowned experts within the UPMC Digestive Disorders Center.